It is a popular misconception that every poison has an antidote fopr treatment, However, this is often not the case. The routine symptomatic medical management remain the mainstream for most poisons, especially if the poisons has not been identified. If the poison is ingested up to two hours, gastric demontamination ( Induced emesis, gastric lavage or aspiration or administration of activated charcoal) may be carried out to prevent further absorption of poison.

Opiate(including  morphine, methadone) Toxicity:

Naloxone , an short acting opiate antagonist, whoich can antagonise the effect of opiate, including the respratory depression and its euphoriant effects. It must be given a sufficiently large initial dose (800 ug to 1200ug) and because of its short duration of action, doese must be repeated frequently or given by infusion.  In faxct it is empolyed as a diagnostic tool of opiate poisoning.

Benzodiazepine:

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Poison------------------------------------------------------------------------------------------Antidotes

 Acetominophen                                                                                              NAC(N-acetylcysteine)
 Anticholinergics                                                                                            Physostigmine
 Anticoagulants (warfarin/coumadin,heparin)                                                    Vitamin K1, protamine.
 Benzodiazepines                                                                                            Supportive Care, &
                                                                                                                     Flumazenil*
 Botulism                                                                                                        Botulinum Antitoxin
 Beta Blockers                                                                                                Glucagon
 Calcium Channel Blockers                                                                                Calcium, ?Glucagon?
 Cholinergics /organophosphate insecticides/some nerve gases                            Atropine, &
                                                                                                                      Pralodixime in
                                                                                                                      Organophosphate
                                                                                                                      Overdose
 Carbon Monoxide                                                                                            Oxygen, Hyperbaric
                                                                                                                      Oxygen
 Cyanide                                                                                                          Amyl Nitrate,
                                                                                                                      Sodium Nitrate,
                                                                                                                      Sodium Thiosulfate,
                                                                                                                      Hydroxycobalamin
                                                                                                                      (Available in Europe).
 Digoxin                                                                                                          Digoxin Fab
                                                                                                                      Antibodies
 Iron                                                                                                               Deferoxamine
 Isoniazid                                                                                                        Pyridoxine
 Lead                                                                                                               BAL, EDTA, DMSA
 Methemoglobinemia                                                                                          Methelene Blue
 Opiods                                                                                                            Naloxone
 Toxic Alcohols                                                                                                 Ethanol Drip,
                                                                                                                       Dialysis.
Tricycluc Antidepressant                                                                                  Barbiturate &
                                                                                                                       Sodium
                                                                                                                       Bicarbonate
*Use of flumazenil contraindicated in many situations including tricyclic overdose or in chronically habituated benzodiazepine users, as this may precipitate seizures.